Browsing by Author "Fikriye Polat"
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Analysis of Ki-ras exon 2 gene mutations in 3-methylcholanthrene and butylated hydroxytoluene-ınduced rat lung tissues
Fikriye Polat; Öztürk Özdemir; Şahende Elagöz (2008)Bir polisiklik aromatik hidrokarbon ve potansiyel karsinojenik ajan olan MCA, deneysel kanser çalışmalarında sıklıkla kullanılır. BHT, yiyeceklerin tazeliğini, besin değerini, tadını ve rengini sabit tutmak ve korumak için, ... -
The effect of 3-methylcholanthrene and butylated hydroxytoluene on glycogen levels of liver, muscle, testis, and tumor tissues of rats
This study examined the effects of separate and combined applications of 3-methylcholanthrene, a polycyclic aromatic hydrocarbon and potent carcinogenic agent, and butylated hydroxytoluene, the antioxidant food additive, ... -
eNOS gene polymorphisms in paraffin-embedded tissues of prostate cancer patients
Background/aim: The purpose of the present study was to investigate whether endothelial nitric oxide synthase (eNOS) gene polymorphisms play a role in prostate cancer (PCa). Materials and methods: We examined three eNOS ... -
Possible role of DNA hypomethylation in mutagenic activity of N'-Ethyl-N'-Nitrosourea (ENU) on subcutaneous rhabdomyosarcoma in rat
Purpose: The aim of the study was to find out the possible effects of DNA hypomethylation on N'-ethyl-N'-nitrosourea (ENU) mutagenity. Methods: Rats were injected with 300mg/kg body weight-body weight ENU (i.p.)for 45 weeks ...